Yi-Ju Lu, Ph.D.
Ph. D., 2012, Cologne University and Max Planck Institute for Plant Breeding Research, Germany
Ph. D. fellowship, The Sainsbury Lab (TSL), UK
Ph. D. fellowship, Max Planck Institute for plant breeding research, Germany
M. S., 2006, National Taiwan University, department of Plant Pathology and Microbiology, Taiwan
B. S., 2004, National Taiwan University, department of Plant Pathology and Microbiology, Taiwan
Postdoctoral research fellow, 2012-current, Michigan State University, USA
Research assistant, 2008, Agriculture biotechnology research center, Academia Sinica, Taiwan
Research intern, 2003-2004, National Taiwan University, Department of Plant Pathology and Microbiology, Taiwan
I am a molecular plant pathologist and my interest focuses specifically on understanding the mechanisms underlying plant immunity and pathogen virulence targeting of host processes required for immune signaling. During my Ph.D. research at the Max Planck Institute for Plant Breeding Research, I studied the role of subcellular compartments reorganization in different stages of plant-pathogen interactions. This work provided insights into the function and effects of the model downy mildew pathogen-Hyaloperonospora arabidopsidis.
In my current research, I am working on the molecular-genetic analysis of the host-pathogen interface, specifically through the analysis of the host actin cytoskeleton. My research highlights the importance of activation and regulation of resistance signaling through the actin cytoskeleton, using both direct and indirect targeting of the actin cytoskeleton by the bacterial pathogen Pseudomonas syringae. Also I am interested in the regulation of actin dynamics by bacterial effectors.
Lu, Y-J., and Day, B. (2017). Quantitative evaluation of plant actin cytoskeletal parameters during immune signaling. Methods in Mol. Biol. 1578: 207-221.
Shimono, M*., Lu, Y*., Porter, K., Kvitko, B., Creason, A., Henty-Ridilla, J., He, S.Y., Chang, J.H., Staiger, C., and Day, B. (2016). The Pseudomonas syringae type III effector HopG1 induces actin filament remodeling in Arabidopsis in association with disease symptom development. Plant Physiol. 171: 2239-2255. (* Equal contribution).
Lu Y-J*, Schornack S*, Spallek T, Geldner N, Chory J, Schellmann S, Schumacher K, Kamoun S, and Robatzek S. (2012). Patterns of plant subcellular responses to successful oomycete infections reveal differences in host cell reprogramming and endocytic trafficking. Cell Microb. 14(5):682-97. (* Equal contribution).