Welcome to the laboratory of Dr. Brad Day at Michigan State University. Research in the Day lab focuses on the molecular-genetic and biochemical processes associated with the interaction between plants and pathogens.
Specifically, we are interested in how plants protect themselves from pathogen infection using both preformed and induced defense responses. Using a combination of cell biology and genetics, we are investigating how the actin cytoskeleton impacts defense signaling in the model system Arabidopsis thaliana.
We are also using genetics and biochemistry to ask how gene-for-gene resistance signaling is initiated during the early stages of the host-pathogen association.
Finally, a recent project in the lab aims to understand how the downy mildew pathogen Pseudoperonospora cubensis interacts with cucumber. This work involves a combination of genomics, cell biology and chemistry to dissect the events critical to the onset of resistance in cucumber. More details about projects, people and future directions can be found throughout this webpage.